Ariadne (drug)

Common card · No. 379190

Ariadne, also known chemically as 4C-D or 4C-DOM, by its developmental code name BL-3912, and by its former tentative brand name Dimoxamine, is a non-hallucinogenic psychoactive drug of the phenethylamine, phenylisobutylamine (α-ethylphenethylamine), and 4C families. It is a close analogue of the psychedelic drugs 2C-D and DOM, with 2C-D having no substitution at the α carbon, DOM having an α-methyl group, and Ariadne having an α-ethyl group. Ariadne is taken orally. The drug is a serotonin 5-HT2 receptor partial agonist, including of the serotonin 5-HT2A receptor, similarly to psychedelics. However, Ariadne is not hallucinogenic in humans, but is still psychoactive, producing antidepressant and mild stimulant effects such as feelings of well-being and mental alertness. The drug shows dopaminergic actions in animals, such as increased motivation and reversal of parkinsonism, which may be mediated by serotonin 5-HT2A receptor activation-induced dopamine release in the brain. It is thought...

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