Clobetasol propionate

Uncommon card · No. 156816

Clobetasol propionate is a corticosteroid that is used to treat skin conditions such as eczema, contact dermatitis, seborrheic dermatitis, steroid responsive dermatosis, and psoriasis (including scalp and plaque-type). It is applied to the skin as a cream, foam, gel, liquid, solution, ointment, or shampoo. Clobetasol propionate is a propionate ester of the corticosteroid clobetasol. Common side effects include skin irritation, dry skin, redness, pimples, and telangiectasia. More serious side effects include allergic reactions, cellulitis, adrenal suppression and Cushing's syndrome. Use in pregnancy and breastfeeding is of unclear safety. Clobetasol is believed to work by activating steroid receptors. Clobetasol propionate was patented in 1968 and came into medical use in 1978. It is available as a generic medication. In 2023, it was the 129th most commonly prescribed medication in the United States, with more than 4 million prescriptions.

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