Tamoxifen

Uncommon card · No. 167386

Tamoxifen, marketed under the brand name Nolvadex (among others), is a selective estrogen receptor modulator sometimes used in breast cancer drug regimens for women and men. It is also being studied for other types of cancer. It has been used for Albright syndrome. Tamoxifen is usually administered orally for five years for breast cancer. Serious side effects of tamoxifen can include increased risk of uterine cancer, stroke, ophthalmological problems, and pulmonary embolisms. Common side effects include irregular periods, weight loss, and hot flashes. It may cause harm to a foetus if taken during pregnancy or breastfeeding. Tamoxifen is a selective estrogen-receptor modulator (SERM) and works by decreasing the growth of breast cancer cells. It is a member of the triphenylethylene group of compounds. Tamoxifen was first sythesized in 1962 by chemist Dora Richardson. It is on the World Health Organization's List of Essential Medicines. Tamoxifen is available as a generic medication. In 2020...

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