Common

Lactulose

Treatment for constipation and hepatic encephalopathy

Lactulose

Common card · No. 233092

Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy. It is administered orally for constipation, and either orally or rectally for hepatic encephalopathy. It generally begins working after 8–12 hours, but may take up to 2 days to improve constipation. Common side effects include abdominal bloating and cramps. A potential exists for electrolyte problems as a result of the diarrhea it produces. No evidence of harm to the fetus has been found when used during pregnancy. It is generally regarded as safe during breastfeeding. It is classified as an osmotic laxative. Lactulose is a disaccharide composed of galactose and fructose, which are simple sugars. It is made from the milk sugar lactose, which is a disaccharide of the simple sugars galactose and glucose. Lactulose was first made in 1929, and has been used medically since the 1950s. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication...

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