Macrogol

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Macrogol is the international nonproprietary name used for polyethylene glycol (PEG) as a medication ingredient. It is usually followed by a number indicating the average molecular weight, indicating the length of the polymer of the specific molecule in use. Macrogol is used as a laxative to treat constipation in children and adults. It is orally administered, with a resultant bowel movement typically occurring within a few days. Larger dose are used to clear the bowels, as preparation prior to a colonoscopy; the onset of the laxative effect is more rapid at this dosage, with onset typically within an hour and lasting for up to a few days. Small amounts are also used as a non primary ingredient in medication. Side effects may include increased flatulence, abdominal pain, and nausea. Rare but serious side effects may include an abnormal heartbeat, seizures, and kidney problems. Moderate usage appears to be safe during pregnancy. It is classified as an osmotic laxative: It works by increasing...

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