La Crosse, Wisconsin
City and county seat of La Crosse County, Wisconsin
La Crosse, Wisconsin
La Crosse ( lə-KROSS) is a city in La Crosse County, Wisconsin, United States, and its county seat. Positioned alongside the Mississippi River, La Crosse is the most populous city on Wisconsin's western border. The population was 52,680 at the 2020 census. The La Crosse–Onalaska metropolitan area has an estimated 140,000 residents. La Crosse serves as a regional educational, medical, manufacturing, and transportation hub for Western Wisconsin producing a gross domestic product (GDP) of $10.1 billion for the La Crosse–Onalaska metropolitan area as of 2023. Home to the University of Wisconsin–La Crosse, Viterbo University, and Western Technical College, the city has nearly 20,000 students. The La Crosse area is home to the headquarters or regional offices of Kwik Trip, Organic Valley, Mayo Clinic, Gundersen Health System, Gensler, La Crosse Technology, City Brewing Company, and Trane.
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