Enantioselective synthesis
Chemical reaction(s) which favor one chiral isomer over another
Enantioselective synthesis
Enantioselective synthesis, also called asymmetric synthesis, is a form of chemical synthesis. It is defined by IUPAC as "a chemical reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric products in unequal amounts." That is, it is the synthesis of a chemical by a method that favors the formation of a specific stereoisomer among several possibilities. Enantioselective synthesis is a key process in modern chemistry and is particularly important in the field of pharmaceuticals, as the different enantiomers or diastereomers of a structure often have different biological activity.
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