Trisomy 16

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Trisomy 16 is a chromosomal abnormality in which there are 3 copies of chromosome 16 rather than two. It is the most common autosomal trisomy leading to miscarriage, and the second most common chromosomal cause (closely following X-chromosome monosomy). About 6% of miscarriages have trisomy 16. Those mostly occur between 8 and 15 weeks after the last menstrual period. A child cannot be born alive with an extra copy of this chromosome present in all cells (full trisomy 16). It is possible, however, for a child to be born alive with the mosaic form.

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