Silibinin

Common card · No. 474882

Silibinin (INN), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others. Silibinin itself is a mixture of two diastereomers, silybin A and silybin B, in approximately equimolar ratio. In some European countries, silibinin is available as part of the silymarin extract for oral use and as a water solution containing the dihemisuccinate disodium salt for intravenous injection. The extract is also available in other regions as a dietary supplement.

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