
Schistocyte
Fragmented portion of a red blood cell

Fragmented portion of a red blood cell
A schistocyte (from Greek schistos for "divided" and kytos for "hollow" or "cell") is a fragmented part of a red blood cell. Several microangiopathic diseases, including disseminated intravascular coagulation and thrombotic microangiopathies, generate fibrin strands that sever red blood cells as they try to move past a thrombus, creating schistocytes. Schistocytes are often seen in patients with hemolytic anemia. They are frequently a consequence of mechanical artificial heart valves, aortic stenosis, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura, among other causes. Excessive schistocytes present in blood can be a sign of microangiopathic hemolytic anemia (MAHA).
Read on Wikipedia · Image Central Hematology Laboratory Hemostasis Research Laboratory Bern University Hospital & University of Bern, CC BY-SA 4.0
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