Statin
Class of drugs to lower cholesterol
Statin
Statins (or HMG-CoA reductase inhibitors) are a class of medications that lower the concentration of cholesterol in the blood. They are typically prescribed to people who are at high risk of cardiovascular disease. Low-density lipoprotein (LDL) carriers of cholesterol play a key role in the development of atherosclerosis and coronary heart disease via the mechanisms described by the lipid hypothesis. As lipid-lowering medications, statins are effective in lowering apolipoprotein B and LDL cholesterol; they are widely used for primary prevention in people at high risk of cardiovascular disease, as well as in secondary prevention for those who have cardiovascular disease. Statins reduce the risk of myocardial infarction and stroke. Side effects of statins include an increased risk of muscle pain, a slightly increased risk of diabetes, and abnormal blood levels of certain liver enzymes in some people. Additionally, they rarely cause severe adverse effects, particularly muscle damage, and very...
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