Systemic vasculitis

Common card · No. 391807

Necrotizing vasculitis, also called systemic necrotizing vasculitis, is a general term for the inflammation of veins and arteries that develops into necrosis and narrows the vessels. Tumors, medications, allergic reactions, and infectious organisms are among the recognized triggers for these conditions, though the precise cause of many is unknown. Immune complex disease, anti-neutrophil cytoplasmic antibodies, anti-endothelial cell antibodies, and cell-mediated immunity are examples of pathogenetic factors. Numerous secondary symptoms of vasculitis can occur, such as blood clots, the formation of weak bulging areas in blood vessel walls (aneurysms), bleeding, blockage (occlusion) of an artery, unintentional weight loss, exhaustion, depression, fever, and widespread pain that worsens in the morning. Systemic vasculitides are categorized as small, medium, large, or variable based on the diameter of the blood vessel they primarily affect.

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