
Nerve agent
Class of organophosphates; classified as weapons of mass destruction

Class of organophosphates; classified as weapons of mass destruction
Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that catalyzes the breakdown of acetylcholine, a neurotransmitter. Nerve agents are irreversible acetylcholinesterase inhibitors used as poison. Poisoning by a nerve agent leads to constriction of pupils, profuse salivation, convulsions, and involuntary urination and defecation, with the first symptoms appearing in seconds after exposure. Death by asphyxiation or cardiac arrest may follow in minutes due to the loss of the body's control over respiratory and other muscles. Standard treatment for nerve agent poisoning is a combination of an anticholinergic to manage the symptoms, and an oxime as an antidote. The most mass-produced nerve agents in history are VX/VR, sarin, and soman. The G-series consists of the earliest nerve agents discovered from the late...
Read on Wikipedia · Image Valentin Müller, CC BY-SA 3.0
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