
Optic neuritis
Inflammation of the optic nerve

Inflammation of the optic nerve
Optic neuritis (ON) is a debilitating condition that is defined as inflammation of cranial nerve II which results in disruption of the neurologic pathways that allow visual sensory information received by the retina to be able to be transmitted to the visual cortex of the brain. This disorder of the optic nerve may arise through various pathophysiologic mechanisms, such as through demyelination or inflammation, leading to partial or total loss of vision. Optic neuritis may be a result of standalone idiopathic disease, but is often a manifestation that occurs secondary to an underlying disease. Signs of ON classically present as sudden-onset visual impairment in one or both eyes that can range in severity from mild visual blurring to complete blindness in the affected eye(s). Although pain is typically considered a hallmark feature of optic neuritis, the absence of pain does not preclude a diagnosis or consideration of ON as some patients may not report any pain. ON is typically subtyped...
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