Neonatal jaundice

Common card · No. 354912

Neonatal jaundice, clinically known as neonatal hyperbilirubinemia and icterus neonatorum, is the yellowish discoloration of the white part of the eyes (sclerae) and skin in newborn infants caused by an elevated concentration of bilirubin in the blood (hyperbilirubinemia). It is one of the most frequently encountered medical conditions in the neonatal period, affecting approximately 60% of term and 80% preterm newborns within the first week of life. Globally, over 100,000 late-preterm and term babies die each year as a result of jaundice, particularly in low- and middle-income countries. Bilirubin is a yellow-orange pigment naturally produced during the breakdown of red blood cells. While mild jaundice in newborns is generally harmless and self-resolving, elevated bilirubin levels, if left untreated, can cross the blood-brain barrier to cause permanent neurological damage. The condition is known as kernicterus or chronic bilirubin encephalopathy (CBE). Neonatal jaundice has been described...

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