Common
Orthopoxvirus
Genus of viruses (poxes)
Genus of viruses (poxes)
Orthopoxvirus is a genus of viruses in the family Poxviridae and subfamily Chordopoxvirinae. Vertebrates, including mammals and reptiles, and arthropods serve as natural hosts. There are 12 known species in this genus. Diseases associated with this genus include smallpox, cowpox, horsepox, camelpox, and mpox (monkeypox). The most widely known member of the genus is Variola virus, which causes smallpox. It was eradicated globally by 1977, through the use of Vaccinia virus as a vaccine. The most recently described species of orthopoxvirus is the Borealpox virus, first isolated in 2015.
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