Bullous pemphigoid
Autoimmune disease of skin and connective tissue characterized by large blisters
Bullous pemphigoid
Bullous pemphigoid (a type of pemphigoid) is an autoimmune pruritic skin disease that typically occurs in people aged over 60, that may involve the formation of blisters (bullae) in the space between the epidermal and dermal skin layers. It is classified as a type II hypersensitivity reaction, which involves the formation of anti-hemidesmosome antibodies, causing a loss of keratinocytes to basement membrane adhesion.
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