Variably protease-sensitive prionopathy

Common card · No. 481432

Variably protease-sensitive prionopathy (VPSPr) (formerly known as protease sensitive prionopathy) is a sporadic transmissible spongiform encephalopathy first described in an abstract for a conference on prions in 2006. The study was published in a 2008 report on 11 cases. It was first identified as a distinct disease in 2010 by Zou W.Q. and coworkers from the United States National Prion Disease Pathology Surveillance Center. VPSPr shares similarities to other neurodegenerative disorders such as Creutzfeldt-Jakob disease and Alzheimer's, but there are unique markers of the disease in its clinical manifestations and electrophoretic profile.

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