Common

Leser–Trélat sign

Onset of multiple seborrheic keratoses

Leser–Trélat sign

Common card · No. 435603

The Leser–Trélat sign is the explosive onset of multiple seborrheic keratoses (many pigmented skin lesions), often with an inflammatory base. This can be a sign of internal malignancy as part of a paraneoplastic syndrome. In addition to the development of new lesions, preexisting ones frequently increase in size and become symptomatic.

Read on Wikipedia · Image James Heilman, MD, CC BY-SA 3.0

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