Common
Evolocumab
Pharmaceutical drug
Evolocumab
Evolocumab, sold under the brand name Repatha, is a monoclonal antibody drug. It is an immunotherapy medication for the treatment of hyperlipidemia. Evolocumab inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 is a protein that targets LDL receptors for degradation; its inhibition enhances the liver's ability to remove LDL-C, the "bad" cholesterol, from the blood. In 2023, it was the 188th most commonly prescribed medication in the United States, with more than 2 million prescriptions.
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