Auto-brewery syndrome
Medical condition in which the gut produces excess alcohol
Auto-brewery syndrome
Auto-brewery syndrome (ABS) (also known as gut fermentation syndrome or endogenous ethanol fermentation) is an extremely rare and underdiagnosed medical condition characterized by the fermentation of ingested carbohydrates in the gastrointestinal tract caused by bacteria or fungi. Intoxicating amounts of ethanol are produced through endogenous fermentation within the digestive system. The organisms responsible for ABS include various yeasts and bacteria, including Saccharomyces cerevisiae, S. boulardii, Candida albicans, C. tropicalis, P. kudriavzevii, N. glabratus, C. parapsilosis, Kluyveromyces marxianus, Klebsiella pneumoniae, and Enterococcus faecium. These organisms undergo lactic acid fermentation or mixed acid fermentation pathways to produce an ethanol end product. The ethanol generated from these pathways is absorbed in the small intestine and stomach, raising blood alcohol concentrations and causing the effects of intoxication without the ingestion of alcohol. Researchers suggest...
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