Chlamydia trachomatis

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Chlamydia trachomatis () is a Gram-negative, facultative anaerobic bacterium responsible for chlamydia and trachoma. C. trachomatis exists in two forms, an extracellular infectious elementary body (EB) and an intracellular non-infectious reticulate body (RB). The EB attaches to host cells and enter the cell using effector proteins, where it transforms into the metabolically active RB. Inside the cell, RBs rapidly replicate before transitioning back to EBs, which are then released to infect new host cells. The earliest description of C. trachomatis was in 1907 by Stanislaus von Prowazek and Ludwig Halberstädter as a protozoan. It was later thought to be a virus due to its small size and inability to grow in laboratories. It was not until 1966 when it was discovered as a bacterium by electron microscopy after its internal structures were visually observed. There are currently 18 serovars of C. trachomatis, each associated with specific diseases affecting mucosal cells in genital tracts and...

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