Henry Molaison

Uncommon card · No. 104599

Henry Gustav Molaison (February 26, 1926 – December 2, 2008), known widely as H.M., was an American epileptic man who in 1953 received a bilateral medial temporal lobectomy to surgically resect parts of his brain—the anterior two thirds of his hippocampi, parahippocampal cortices, entorhinal cortices, piriform cortices, and amygdalae—in an attempt to cure his epilepsy. Although the surgery was partially successful in controlling his epilepsy, a severe side effect was that he became unable to form new memories. A childhood bicycle accident is often advanced as the likely cause of H.M.'s epilepsy. H.M. began to have minor seizures at age 10; from 16 years of age, the seizures became major. Despite high doses of anticonvulsant medication, H.M.'s seizures were incapacitating. When he was 27, H.M. was offered an experimental procedure by neurosurgeon William Beecher Scoville. Previously, Scoville had only ever performed the surgery on psychotic patients. H.M. was extensively studied from late...

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