Histamine intolerance

Common card · No. 346981

Histamine intolerance is a presumed set of adverse reactions (such as flushing, itching, rhinitis, etc.) to ingested histamine in food. The mainstream theory accepts that there may exist adverse reactions to ingested histamine, but does not recognize histamine intolerance as a separate medical condition that can be diagnosed. Some believe that ingested histamine in persons with deficiencies in the enzymes that metabolize histamine may be responsible for various non-specific health complaints, which some individuals categorize as histamine intolerance. However, histamine intolerance is not recognized as a diagnosable condition in the International Classification of Diseases, 11th Revision (ICD-11). The scientific evidence of a direct causal relationship between ingested histamine and reproducible symptoms is currently limited and inconsistent. Histamine intolerance reportedly affects a variable portion of the population, with estimates on about 1%, though exact prevalence is unclear due...

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