Zuranolone

Common card · No. 309479

Zuranolone, sold under the brand name Zurzuvae, is a medication used for the treatment of postpartum depression and major depressive disorder. It is taken orally. Zuranolone is a neuroactive steroid which enhances the activity of the neurotransmitter γ-aminobutyric acid (GABA) and is thought to exert antidepressant effects by enhancing GABAergic inhibition. The most common side effects include drowsiness, dizziness, diarrhea, fatigue, nasopharyngitis, and urinary tract infection. Zuranolone was approved for medical use in the United States for the treatment of postpartum depression in August 2023. It was developed by Sage Therapeutics and Biogen.

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