Pierre Robin sequence

Common card · No. 367263

Pierre Robin sequence (; abbreviated PRS), also known as Pierre Robin syndrome, is a congenital defect observed in humans which is characterized by facial abnormalities. The three main features are micrognathia (abnormally small mandible), which causes glossoptosis (downwardly displaced or retracted tongue), which in turn causes breathing problems due to obstruction of the upper airway. A wide, U-shaped cleft palate is commonly also present. PRS is not merely a syndrome, but rather it is a sequence: a series of specific developmental malformations which can be attributed to a single cause.

Read on Wikipedia · Image Sydney S. Gellis and Murray Feingold, Public domain