Liposome

Common card · No. 334504

A liposome is a small artificial vesicle, spherical in shape, having at least one lipid bilayer. Due to their hydrophobicity and/or hydrophilicity, biocompatibility, particle size and many other properties, liposomes can be used as drug delivery vehicles for administration of pharmaceutical drugs and nutrients, such as lipid nanoparticles in mRNA vaccines, and DNA vaccines. Liposomes can be prepared by disrupting biological membranes (such as by sonication). A nanoliposome or nanoliposomal vehicle is a liposome in the nanoscale; in other words, it is a kind of nanocarrier involved in the processes of nanoencapsulation and nanodelivery. Another kind of lipid-based nanocarrier similar to the nanoliposome is the nanocochleate; however, whilst nanoliposomes have a roughly spherical shape, a nanocochleate has a cylindrical (cigar-like) microstructure created by spirally rolled bilayers in which drugs (e.g., hydrophobic and hydrophilic biomolecules) are nanoincapsulated. Liposomes are most...

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