Phenazolam

Common card · No. 449400

Clobromazolam (also known as phenazolam, DM-II-90, and BRN 4550445) is a synthetic benzodiazepine derivative. It is structurally related to other triazolobenzodiazepines and is believed to act as a potent sedative and hypnotic through positive allosteric modulation of the GABAA receptor. The compound was first described in the early 1980s during research into novel anxiolytic and hypnotic agents, but it was never developed or approved for medical use. Clobromazolam has emerged in the 21st century as a designer drug, being sold online and detected in forensic casework. It was first identified in seized samples by a Swedish laboratory in March 2016. Due to its high potency and lack of clinical evaluation, its use has been associated with significant safety concerns, including the risk of overdose, dependence, and severe central nervous system depression.

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