History of COVID-19 vaccine development

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SARS-CoV-2, the virus that causes COVID-19, was isolated in late 2019. Its genetic sequence was published on 11 January 2020, setting off an intense research effort to develop a COVID-19 vaccine. Vaccine development was expedited via unprecedented collaboration between academia, the pharmaceutical industry and governments. By June 2020, tens of billions of dollars were being invested to develop dozens of vaccine candidates and prepare for global vaccination programs. According to the Coalition for Epidemic Preparedness Innovations (CEPI), the geographic distribution of COVID‑19 vaccine development shows North American entities to have about 40% of the activity, compared to 30% in Asia and Australia, 26% in Europe, and a few projects in South America and Africa. In February 2020, the World Health Organization (WHO) said it did not expect a vaccine against SARS‑CoV‑2 to become available in less than 18 months. Virologist Paul Offit commented that, in hindsight, the development of a safe...

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