Chromatin
Complex of DNA and protein in eukaryotic cells
Complex of DNA and protein in eukaryotic cells
Chromatin is a complex of DNA and protein responsible for condensing and packaging chromosomal DNA. Chromatin is found in both bacterial and eukaryotic cells. Eukaryotic chromatin consists primarily of DNA associated with histone proteins and numerous other chromatin-binding factors that contribute to genome organization and regulation. Chromatin packages long DNA molecules into compact structures while controlling access to genetic information for processes such as transcription, DNA replication, and DNA repair. During cell division, chromatin facilitates proper segregation of chromosomes in anaphase; the characteristic shapes of chromosomes visible during this stage are the result of DNA being coiled into highly condensed chromatin. Chromatin organization is often described at several structural levels. At the most basic level, DNA wrapped around histone octamers forms nucleosomes connected by stretches of linker DNA, producing a structure sometimes referred to as a "beads-on-a-string...
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