Craniodiaphyseal dysplasia

Uncommon card · No. 101908

Craniodiaphyseal dysplasia (CDD), also known as lionitis, is an extremely rare autosomal recessive bone disorder that causes calcium to build up in the skull, disfiguring the facial features and reducing life expectancy. These calcium deposits reduce the size of cranial foramen, and can decrease the circumference of the cervical spinal canal. In the few cases recorded, most died in childhood.