Henoch–Schönlein purpura

Common card · No. 216041

IgA vasculitis, previously known as Henoch–Schönlein purpura (HSP), is an autoimmune disease that most commonly affects children. In the skin, the disease causes palpable purpura (small, raised areas of bleeding underneath the skin), often with joint pain (arthralgia) and abdominal pain. With kidney involvement, there may be a loss of small amounts of blood and protein in the urine (hematuria and proteinuria), but this usually goes unnoticed; in a small proportion of cases, the kidney involvement proceeds to chronic kidney disease (CKD). HSP is often preceded by an infection, such as a throat infection. HSP is a systemic vasculitis (inflammation of blood vessels) and is characterized by deposition of immune complexes containing the antibody immunoglobulin A (IgA); the exact cause for this phenomenon is unknown. In children, it usually resolves within several weeks and requires no treatment apart from symptom control but may relapse in 1 out of 3 cases and cause irreversible kidney damage...

Read on Wikipedia · Image Madhero88, CC BY-SA 3.0