American Dad! season 22

Uncommon card · No. 84025

American Dad!'s twenty-second season premiered on Fox on February 22, 2026, marking the show's return to the network following its cancellation by TBS in March 2025. The season features guest appearances from Ming-Na Wen, RuPaul, Chris Pine, Bradley Whitford, Patrick Stump, Jonathan Frakes, Joe Mantegna, Wayne Newton, Kyle MacLachlan, Mary Steenburgen and Ted Danson. The season concluded on September 13, 2026. The series focuses on the eccentric upper middle class Smith family, consisting of father, husband, CIA agent, and Republican, Stan; his wife and housewife, Francine; their liberal, hippie, college-aged daughter, Hayley-Fischer; their dorky high-school-aged son, Steve; the family's unusual goldfish, Klaus; flamboyant, master of disguise alien, Roger; Jeff Fischer, Hayley Smith's stoner husband who resides with the Smith family; and Roger's ex-tumor son Rogu, who reside in a fictionalized version of Langley, Virginia. This season contains "400?!", the 400th episode of the series which...

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