
Mephenaqualone
Pharmaceutical compound

Pharmaceutical compound
Mephenaqualone is an analogue of the sedative and hypnotic drug methaqualone which has been sold as a designer drug. It was reported in Germany in 2025 as a contributor to drug overdose cases but has otherwise been little studied. Anecdotal reports suggest it is considerably more potent than methaqualone with a potency similar to that of benzodiazepine derivatives, but no pharmacological data is available as yet. It is reported to have a dose of 0.7–0.8 mg or 2 mg orally and to produce sedative, hypnotic, euphoric, anxiolytic, and pro-sexual effects among others. Its onset is 20 minutes and its duration is approximately 4 to 10 hours.
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