Linoleic acid
18-Carbon polyunsaturated fatty acid
18-Carbon polyunsaturated fatty acid
Linoleic acid (LA) is an organic compound with the formula CH3(CH2)4CH=CHCH2CH=CH(CH2)7COOH. Both alkene groups (−CH=CH−) are cis. It is a fatty acid sometimes denoted 18:2 (n−6) or 18:2 cis-9,12. A linoleate is a salt or ester of this acid. Linoleic acid is a polyunsaturated, omega−6 fatty acid. It is a colorless liquid that is virtually insoluble in water but soluble in many organic solvents. It typically occurs in nature as a triglyceride (ester of glycerin) rather than as a free fatty acid. It is one of two essential fatty acids for humans, who must obtain it through their diet, and the most essential, because the body uses it as a base to make the others. Linoleic acid intake is associated with lowering the risk of cardiovascular disease. The word "linoleic" derives from Latin linum 'flax' and oleum 'oil', reflecting the fact that it was first isolated from linseed oil.
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