Fatty acid synthesis
Biochemical process in which fatty acids are derived from acetyl-CoA and NADPH
Fatty acid synthesis
In biochemistry, fatty acid synthesis is the process by which fatty acids, the fundamental building blocks of fats, are derived from metabolic intermediates through the coordinated actions of enzymes. Fatty acids (FAs), comprise a large group of chemically heterogeneous compounds. Each fatty acid is composed of a carboxylic acid attached to an aliphatic hydrocarbon chain, of which is either saturated or unsaturated. FAs prove crucial within the cell, as these molecules serve as the indispensable building blocks of cell membranes. FAs also provide dense, long-term energy sources for the cell, and the biosynthetic production of FAs is essential for maintaining cellular homeostasis. Fatty acid biosynthetic pathways are highly evolutionarily conserved across species, though different enzymes and genetic organizations have evolved to reach similarities about the general pathway. In both animals and fungi, all fatty acid synthetic pathways utilize one multifunctional protein complex, type-I...
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